IFN-y Recombinant eiwit
Gecertificeerd

IFN-y Recombinant eiwit

Catalog #: 40-557
Maat: 0.1 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Technische Documentatie

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Technische Specificaties

Background

IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant human IFN-γ is a 16.7 kDa protein containing 143 amino acid residues.Manufactured using all non-animal reagents.

NCBI Gene ID

3458

Swiss Prot

P01579

Accession Number

NP_000610.2

Type

Recombinant Proteins

Source

E. coli

Field of Research

Chemokines & Cytokines, Growth Factors, Immunology, Innate Immunity

Purity

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Shipping Conditions

Room Temp

Storage Conditions

The lyophilized IFN-y recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IFN-y stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IFN-y recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

NCBI Official Name

Interferon, gamma

NCBI Organism

Homo sapiens

Other Product Names

IFG, IFI, Interferon gamma, Immune interferon, IFN-gamma

Species

Human

Protein ID

56786138

Physical Properties

Lyophilized

CAS Number

9000-83-3