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Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant rat IL-7 is a 15.0 kDa protein containing 130 amino acid residues
Il7
25647
Q91Y32
NP_037242.2
NM_013110
2q23
Rat
Mouse
MDCHIKDKDG KAFGSVLMIS INQLDKMTGT DSDCPNNEPN FFKKHLCDDT KEAAFLNRAA RKLRQFLKMN ISEEFNDHLL RVSDGTQTLV NCTSKEEKTI KEQKKNDPCF LKRLLREIKT CWNKILKGSI
< 0.1 ng/µg of protein (< 1EU/µg)
> 98% by SDS-PAGE & HPLC analyses
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 106 units/mg.
130
Lyophilized
15 kDa
E. coli
Beschrijving
IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can al
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