1-Butyl-3,5,8-trihydroxy-9,10-antraceendion

1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione (Compound 2) is an anthraquinone analog. 1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione can be isolated from soil Actinomycete Streptomyces. 1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione has potent cytotoxicity against HepG2, A875, BGC-823 and MCF-7 cells with IC50s of 2.29, 4.90, 0.99 and 1.66 μg/mL, respectively. 1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione has an antitumor activity[1].

1644075-01-3

12352005

Others

Others

Cancer

O=C1C2=CC(O)=CC(CCCC)=C2C(C3=C1C(O)=CC=C3O)=O

C18H16O5

312.32

[1]Wu ZY, et al. New cytotoxic alkylated anthraquinone analogues from a soil actinomycete Streptomyces sp. WS-13394. Chem Pharm Bull (Tokyo) . 2014;62 (1) :118-21.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N16377/

Natural Products

No Development Reported