1-prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazool

1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole (Compound 19) is a carbazole alkaloid that can be isolated from Murraya koenigii. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole exhibits anti-inflammatory and antimicrobial activities. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole can inhibit the production of pro-inflammatory cytokines TNF-α and IL-6 . 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole has IC50 values of 10.9 μM and 95 μM for Bacillus cereus and Staphylococcus aureus, respectively. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole can be used in the research of inflammatory and infectious diseases[1].

484678-79-7

12352005

Bacterial; Interleukin Related

Anti-infection; Immunology/Inflammation

Infection; Inflammation/Immunology

O=CC1=CC(O)=C2NC3=C(C2=C1)C=CC(OC)=C3C/C=C(C)\C

C19H19NO3

309.36

[1]Nalli Y, et al. Four new carbazole alkaloids from Murraya koenigii that display anti-inflammatory and anti-microbial activities. Org Biomol Chem. 2016 Mar 28;14 (12) :3322-32.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N13828/

Natural Products

No Development Reported

IL-6