10074-G5
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Inhibits c-Myc by disrupting c-Myc/Max heterodimer formation and inhibiting its transcriptional activity.1 10074-G5 binds to the c-Myc bHLHZip domain with Kd=2.8 mM.1 It was cytotoxic in C-Myc-overexpressing cell lines (IC50s = 13 to 15 mM) but was not active in vivo due to rapid metabolism.2 10074-G5 is a useful tool to probe for involvement of c-Myc involvement in cellular processes.3,4 Binds to and sequesters the intrinsically disordered amyloid-β (Aβ) in its monomeric soluble state and rescues a C. elegans model of Aβ-associated toxicity.5
Unconjugated
Orange solid
-20°C
Beschrijving
10074-G5 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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