11-Demethyltomaymycine

11-Demethyltomaymycin is an antibiotic. 11-Demethyltomaymycin has antiviral activity against Escherichia coli T1 and T3 phages and antibacterial activity against Gram-positive bacteria. In addition, 11-Demethyltomaymycin is cytotoxic to leukemia L1210 cells[1][2].

55511-85-8

12352005

Antibiotic; Bacterial

Anti-infection

COVID-19-anti-virus

Cancer; Infection

O=C1N2[C@](C/C(C2)=C\C)([H])[C@H](NC3=CC(O)=C(OC)C=C31)O

C15H18N2O4

290.31

[1]Hurley LH, et al. Pyrrolo[1,4]benzodiazepine antibiotics. Biosynthesis of the antitumor antibiotic 11-demethyltomaymycin and its biologically inactive metabolite oxotomaymycin by Streptomyces achromogenes. Biochemistry. 1976 Aug 24;15 (17) :3760-9.|[2]Hurley L H, et al. Biosynthesis of the antiviral antibiotic 11-demethyltomaymycin by Streptomyces achromogenes. Journal of the Chemical Society, Chemical Communications, 1975 (4) : 120-121.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N14776/

Natural Products

No Development Reported