11-HETE
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
11-HETE (11-Hydroxy-5,8,12,14-eicosatetraenoic acid) is the activator for cytochrome P450. 11-HETE upregulates the mRNA expressions of CYP1B1, CYP1A1, CYP4A11, CYP4F11, and CYP4F2, induces cell hypertrophy in RL-14 cell, and exhibits potential to be used in cardiovascular diseases[1].
73804-65-6
11-Hydroxy-5,8,12,14-eicosatetraenoic acid
12352211
H302-H315-H319-H335
Cytochrome P450
Metabolic Enzyme/Protease
Cardiovascular Disease
CCCCCC=CC=CC(CC=CCC=CCCCC(=O)O)O
C20H32O3
320.47
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
[1]Helal SA, et al., 11-Hydroxyeicosatetraenoics induces cellular hypertrophy in an enantioselective manner. Front Pharmacol. 2024 Aug 12;15:1438567.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W472509/
Reference compound1
No Development Reported
Beschrijving
11-HETE (11-Hydroxy-5,8,12,14-eicosatetraenoic acid) is the activator for cytochrome P450. 11-HETE upregulates the mRNA expressions of CYP1B1, CYP1A1, CYP4A11,
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