1,3-dimethyluracil (standaard)

1,3-Dimethyluracil is a pyrimidone derives from a uracil. 1,3-Dimethyluracil found occasionally in human urine. 1,3-Dimethyluracil shows inhibition activity against hCA I and hCA II (human carbonic anhydrase) with Ki of 316.2 μM and 166.4 μM, respectively[1][2].

874-14-6

12352005

Endogenous Metabolite

Metabolic Enzyme/Protease

Metabolic Disease

CN1C=CC(=O)N(C)C1=O

C6H8N2O2

140.14

[1]Stoessel D, et al. Promising Metabolite Profiles in the Plasma and CSF of Early Clinical Parkinson's Disease. Front Aging Neurosci. 2018 Mar 5;10:51.|[2]Güney M, et al. Synthesis and carbonic anhydrase inhibitory properties of novel uracil derivatives. Bioorg Med Chem Lett. 2015 Aug 15;25 (16) :3261-3.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W008343R/

Reference Standards