14 3 zeta (Ab 58) Antilichaam

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.

7534

P63104

NP_001129171.1

Human, Mouse, Rat

14-3-3 zeta (Ab-58) antibody was raised against a peptide sequence around aa.56~60 (R-S-S-W-R) derived from Human 14-3-3 zeta.

Unconjugated

Primary Antibodies

Apoptosis, Cancer, Cell Cycle

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

28 kDa

This antibody detects endogenous level of total 14-3-3 zeta protein.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

YWHAZ

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

Homo sapiens

Gu YM, et al. (2006) FEBS Lett ; 580 (1) : 305-310Powell DW, et al. (2003) Mol Cell Biol; 23 (15) : 5376-5387Mackintosh C. (2004) Biochem J; 381 (Pt 2) : 329-342.

HEL4, YWHAD, KCIP-1, HEL-S-3, 14-3-3-zeta, ERBB, ERBB1, HER1, 1433Z, 143Z, FAS, Factor activating exoenzyme S

WB, IHC

208973238

Liquid