
(1R,2S,7R) -Sitafloxacine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
(R) -Sitafloxacin (DU-6857), a stereoisomer of Sitafloxacin (DU-6859a), is also an inhibitor of topoisomerases, with an IC50 of 0.18 μg/mL of DNA gyrase[1].
127254-10-8
(1R,2S,7R) -DU-6859a; DU-6857
12352005
Bacterial; Topoisomerase
Anti-infection; Cell Cycle/DNA Damage
COVID-19-anti-virus
Inflammation/Immunology
O=C(C1=CN([C@H]2[C@@H](F)C2)C3=C(C=C(F)C(N(C[C@@H]4N)CC54CC5)=C3Cl)C1=O)O
C19H18ClF2N3O3
409.81
[1]T Akasaka, et al. Antibacterial activities and inhibitory effects of sitafloxacin (DU-6859a) and its optical isomers against type II topoisomerases. Antimicrob Agents Chemother. 1998 May;42 (5) :1284-7.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-B0395D/
Reference compound1
No Development Reported
Beschrijving
(R) -Sitafloxacin (DU-6857), a stereoisomer of Sitafloxacin (DU-6859a), is also an inhibitor of topoisomerases, with an IC50 of 0.18 μg/mL of DNA gyrase[1].
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