
2-ACC
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2-ACC (2-α-Carboxy cholestanol) is a cholestanol, is a mutant Sonic Hedgehog protein D46A activator with an EC50 of ~5 μM.
3091880-01-9
2-α-Carboxy cholestanol
12352100
Hedgehog
Stem Cell/Wnt
Metabolic Disease
C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@H]([C@@H](C2)C(O)=O)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C
C28H48O3
432.68
[1]Ciulla DA, et al. A cell-based bioluminescence reporter assay of human Sonic Hedgehog protein autoprocessing to identify inhibitors and activators. J Biol Chem. 2022 Dec;298 (12) :102705.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N16232/
Natural Products
No Development Reported
Beschrijving
2-ACC (2-α-Carboxy cholestanol) is a cholestanol, is a mutant Sonic Hedgehog protein D46A activator with an EC50 of ~5 μM.
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