2-Acetyl-4-tetrahydroxybutylimidazool-13C6

2-Acetyl-4-tetrahydroxybutyl imidazole-13C6 is the 13C-labeled 2-Acetyl-4-tetrahydroxybutyl imidazole. 2-Acetyl-5-tetrahydroxybutyl imidazole is a potent sphingosine-1-phosphate (S1P) lyase inhibitor in vivo.

1448358-08-4

12352005

Isotope-Labeled Compounds; LPL Receptor

GPCR/G Protein; Others

Inflammation/Immunology

CC(C1=N[13CH]=[13C](N1)[13C@H]([13C@@H]([13C@@H]([13CH2]O)O)O)O)=O

C3 13C6H14N2O5

236.17

[1]Inhibition of Sphingosine-1-Phosphate Lyase for the Treatment of Autoimmune Disorders
 . Med. Chem., 2009, 52 (13), pp 3941-3953; Schwab SR, et al. Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients. Science. 2005 Sep 9;309 (5741) :1735-9.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W779969/

Isotope-Labeled Compounds

No Development Reported