2-Aminochinoline (standaard)

2-Aminoquinoline (2-Quinolinamine) is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline exhibits antiviral activity against the vaccinia virus. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents[1][2].

580-22-3

12352005

NO Synthase; Orthopoxvirus

Anti-infection; Immunology/Inflammation

Infection; Neurological Disease

NC1=NC2=CC=CC=C2C=C1

C9H8N2

144.18

[1]Pensa AV, et al. Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J Med Chem. 2017;60 (16) :7146-7165.|[2]Smee DF, et, al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57 (1-2) :41-52.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W007524R/

Reference Standards