2-Azidoethanol-d4

2-Azidoethanol-d4 is the deuterium labeled Azido-PEG1. Azido-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

12352211

Isotope-Labeled Compounds; PROTAC Linkers

Others; PROTAC

Cancer

OC([2H])(C([2H])(N=[N+]=[N-])[2H])[2H]

C2HD4N3O

91.11

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W743931/

Isotope-Labeled Compounds

No Development Reported