2-CEES

2-CEES is a mustard gas analog forms only DNA monoadducts. 2-CEES induces centrosome amplification in human and mouse cells. 2-CEES induces centrosome amplification and chromosome instability[1].

693-07-2

12352100

H226, H301+H311+H331, H314, H350

DNA/RNA Synthesis

Cell Cycle/DNA Damage

Cancer

98.89

DMSO : ≥ 100 mg/mL

CCSCCCl

C4H9ClS

124.63

H226, H301+H311+H331, H314, H350

[1]Bennett RA, et al. Mustard gas surrogate, 2-chloroethyl ethylsulfide (2-CEES), induces centrosome amplification and aneuploidy in human and mouse cells : 2-CEES induces centrosome amplification and chromosome instability. Cell Biol Toxicol. 2014 Aug;30 (4) :195-205.

Room Temperature

4°C (Powder, stored under nitrogen)

http://file.medchemexpress.com/batch_PDF/HY-W199190/2-CEES-SDS-MedChemExpress.pdf

Reference compound1

No Development Reported