2-Decanon

2-Decanone is an antifungal agent. 2-Decanone inhibits pathogen mycelial growth, spore germination, and appressorium formation. 2-Decanone downregulates spore germination-related genes (MfBmp1) and penetration structure formation genes (MfPls1), inducing reactive oxygen species (ROS) accumulation to trigger mitochondrial damage and subsequent spore apoptosis. 2-Decanone is promising for research of postharvest disease control in fruits and vegetables[1][2].

693-54-9

12352211

H227-H411

Fungal

Anti-infection

Infection

O=C(C)CCCCCCCC

C10H20O

156.27

P210-P273-P280-P370+P378-P391-P403+P235-P501

[1]Hibi M, et al. Attempt to simultaneously generate three chiral centers in 4-hydroxyisoleucine with microbial carbonyl reductases. Bioorg Med Chem. 2018 Apr 1;26 (7) :1327-1332.|[2]Wang X, et al. Antifungal activity of 2-decanone against Monilinia fructicola and its application in combination with boscalid in mitigating brown rot disease in peach fruit[J]. Physiological and Molecular Plant Pathology, 2025, 138: 102665.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W010203/

Natural Products

No Development Reported

Human Endogenous Metabolite