2′-Deoxy-BBP (trinatrium)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2′-Deoxy-GDP (dGDP) trisodium, a guanosine monophosphate (GMP) analogue, is a hypoxanthine phosphoribosyltransferase (HGPRT) inhibitor with an IC50 of 12.5 μM. HGPRT is a central enzyme in the purine recycling pathway of all protozoan parasites[1].
102783-74-4
DGDP (trisodium) ; 2'-Deoxyguanosine-5'-diphosphate (trisodium)
12352005
H315, H319, H335
Nucleoside Antimetabolite/Analog; Parasite
Anti-infection; Cell Cycle/DNA Damage
Infection
98.78
H2O : 50 mg/mL (ultrasonic)
O[C@H]1C[C@H](N(C=N2)C3=C2C(N=C(N)N3)=O)O[C@@H]1COP(OP(O[Na])(O[Na])=O)(O[Na])=O
C10H12N5Na3O10P2
493.15
H315, H319, H335
[1]Md Yousuf Ansari, et al. Establishment of correlation between in-silico and in-vitro test analysis against Leishmania HGPRT to inhibitors. Int J Biol Macromol. 2016 Feb:83:78-96.
Blue Ice
-20°C (Powder, protect from light)
http://file.medchemexpress.com/batch_PDF/HY-W013111/2-Deoxy-GDP-trisodium-SDS-MedChemExpress.pdf
Reference compound2
No Development Reported
Beschrijving
2′-Deoxy-GDP (dGDP) trisodium, a guanosine monophosphate (GMP) analogue, is a hypoxanthine phosphoribosyltransferase (HGPRT) inhibitor with an IC50 of 12.5 μM.
Specificaties
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