2'-Deoxycytidine-13C,15N3

2'-Deoxycytidine-13C,15N3 (Deoxycytidine-13C,15N3) is 13C and 15N labeled 2'-Deoxycytidine. 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu) . 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer[1][2].

Deoxycytidine-13C,15N3; Cytosine deoxyriboside-13C,15N3; Deoxyribose cytidine-13C,15N3

12352005

Endogenous Metabolite; Isotope-Labeled Compounds

Metabolic Enzyme/Protease; Others

Cancer

O=[13C]1[15N](C=CC([15NH2])=[15N]1)[C@H]2C[C@@H]([C@H](O2)CO)O

C8 13CH13 15N3O4

231.19

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Horn D, et al. Inhibition of biological effects of bromodeoxyuridine by deoxycytidine: correlation with decreased incorporation of bromodeoxyuridine into DNA. Somatic Cell Genet. 1976 Sep;2 (5) :469-81.|[3]Iwazaki A, et al. Intravenously administered 2'-deoxycytidine suppresses mouse myeloma tumor growth. Biol Pharm Bull. 2012;35 (2) :251-5.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-D0184S6/

Isotope-Labeled Compounds

No Development Reported