2-Hydroxyaclacinomycine A
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2-Hydroxyaclacinomycin A is an anthracycline antibiotic. 2-Hydroxyaclacinomycin A has the activity of inhibiting leukemia L-1210 cells, and the IC50 for RNA and DNA synthesis is 0.10 μg/mL and 0.95 μg/mL, respectively[1].
79127-36-9
12352005
Antibiotic; Bacterial; DNA/RNA Synthesis
Anti-infection; Cell Cycle/DNA Damage
Cancer; Infection
O=C1C2=C(C(O)=CC(O)=C2)C(C3=C1C=C(C4=C3O)[C@@H](C(OC)=O)[C@@](O)(CC)C[C@@H]4O[C@@H]5O[C@H]([C@H]([C@H](C5)N(C)C)O[C@@H]6O[C@H]([C@H]([C@H](C6)O)O[C@@H]7O[C@H](C(CC7)=O)C)C)C)=O
C42H53NO16
827.87
[1]Y Matsuzawa, et al. Reduction and hydrolysis of 2-hydroxyaclacinomycin A. J Antibiot (Tokyo) . 1981 Nov;34 (11) :1495-7.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N14764/
Natural Products
No Development Reported
Beschrijving
2-Hydroxyaclacinomycin A is an anthracycline antibiotic. 2-Hydroxyaclacinomycin A has the activity of inhibiting leukemia L-1210 cells, and the IC50 for RNA and
Specificaties
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