2-Methylchinazoline-4-ol (standaard)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2-Methylquinazolin-4-ol (Standard) is the analytical standard of 2-Methylquinazolin-4-ol. This product is intended for research and analytical applications. 2-Methylquinazolin-4-ol is a potent competitive poly (ADP-ribose) synthetase inhibitor, with a Ki of 1.1 μM. 2-Methylquinazolin-4-ol mammalian aspartate transcarbamylase (ATCase) inhibitor, with 0.20 mM[1][2].
1769-24-0
12352005
PARP; Reference Standards
Cell Cycle/DNA Damage; Epigenetics; Others
Others
O=C1NC(C)=NC2=C1C=CC=C2
C9H8N2O
160.18
[1]S Yoshida, et al. Production of 2-methyl-4[3H]-quinazolinone, an inhibitor of poly (ADP-ribose) synthetase, by bacterium. J Antibiot (Tokyo) . 1991 Jan;44 (1) :111-2.|[2]Mahmoud Balbaa, et al. Inhibition of mammalian aspartate transcarbamylase by quinazolinone derivatives. J Enzyme Inhib Med Chem. 2008 Aug;23 (4) :483-92.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W051513R/
Reference Standards
Beschrijving
2-Methylquinazolin-4-ol (Standard) is the analytical standard of 2-Methylquinazolin-4-ol. This product is intended for research and analytical applications. 2-M
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