2,3-dihydrothymidine-d3

2,3’-Anhydrothymidine-d3 (2’-Deoxy-3’,2-anhydro-5-methyluridine-d3) is the deuterium labeled 2,3’-Anhydrothymidine. 2,3’-Anhydrothymidine; 2’-Deoxy-3’,2-anhydro-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

2’-Deoxy-3’,2-anhydro-5-methyluridine-d3

12352005

Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog

Cell Cycle/DNA Damage; Others

Cancer

OC[C@H]1O[C@@H]2C[C@H]1OC(N2C=C3C([2H])([2H])[2H])=NC3=O

C10H9D3N2O4

227.23

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W739775/

Isotope-Labeled Compounds

No Development Reported