2,3,5,4'-Tetrahydroxystilbeen-2-O-β-D-glucoside

2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside isolats from the roots of Polygonaceae species, inhibits the formation of 5-HETE, HHT and thromboxane B2. 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside has hypotensive, anti-ageing, anti-inflammatory, hypolipidemic, cardioprotective, and neuroprotective actions[1][2].

82373-94-2

2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside

12352005

H315, H319

ERK; NF-κB

MAPK/ERK Pathway; NF-κB; Stem Cell/Wnt

Neurological Disease; Cardiovascular Disease

99.91

DMSO : 100 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic)

OC1=CC(O)=CC(/C=C/C2=CC=C(O)C=C2)=C1O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO

C20H22O9

406.39

H315, H319

[1]Kimura Y et al. Effects of stilbenes on arachidonate metabolism in leukocytes. Biochim Biophys Acta. 1985 Apr 25;834 (2) :275-8.|[2]Chen Z, et al. 2, 3, 5, 4'-Tetrahydroxystilbene-2-O-β-D-glucoside prevention of lipopolysaccharide-induced depressive-like behaviors in mice involves neuroinflammation and oxido-nitrosative stress inhibition. Behav Pharmacol. 2017 Aug;28 (5) :365-374. |[3]Sun L, et al. Investigation on the mechanism of 2,3,4',5-Tetrahydroxystilbene 2-o-D-glucoside in the treatment of inflammation based on network pharmacology. Comput Biol Med. 2022 Jun;145:105448.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-N0652/2-3-5-4-Tetrahydroxystilbene-2-O-β-D-glucoside-SDS-MedChemExpress.pdf

Natural Products

No Development Reported