2,4-Dinitrobenzeensulfonzuur (natriumzout)

2,4-Dinitrobenzenesulfonic acid (sodium salt) is a hapten. 2,4-Dinitrobenzenesulfonic acid (sodium salt) can induce the proliferation of primary lymphocytes and epithelial cells isolated from guinea pigs that are sensitized to 2, 4-DNCB. 2,4-Dinitrobenzenesulfonic acid (sodium salt) inhibits contact sensitivity induced by 2, 4-DNCB in guinea pigs. 2,4-Dinitrobenzenesulfonic acid (sodium salt) can induce ulcerative colitis in rodent models[1][2][3].

885-62-1

Sodium 2,4-dinitrobenzenesulfonate; DNBS (sodium salt) ; DNBSO (sodium salt)

12352005

H228, H315, H319, H335

Biochemical Assay Reagents

Others

Inflammation/Immunology

99.96

DMSO : 100 mg/mL (ultrasonic)

O=[N+]([O-])C1=CC([N+]([O-])=O)=C(S(=O)(O[Na])=O)C=C1

C6H3N2NaO7S

270.15

H228, H315, H319, H335

[1]Li, Q., & Aoyama, K. (1991) . In vitro evaluation on contact sensitivity from DNCB and DNBS using lymphocyte blastogenesis response test. Sangyo igaku. Japanese journal of industrial health, 33 (6), 509–518. |[2]Frey, J. R., et al., (1971) . Studies on the induction of immunological tolerance by antigen in guinea-pigs already sensitized to dinitrochlorobenzene. Clinical and experimental immunology, 8 (1), 131–139. |[3]Kim, S., et al., (2020) . A Colon-Targeted Prodrug, 4-Phenylbutyric Acid-Glutamic Acid Conjugate, Ameliorates 2,4-Dinitrobenzenesulfonic Acid-Induced Colitis in Rats. Pharmaceutics, 12 (9), 843.

Room Temperature

4°C (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-W324435/2-4-Dinitrobenzenesulfonic-acid-sodium-salt-SDS-MedChemExpress.pdf

Reference compound2

No Development Reported