2,5-Deoxyfructosazine-13C4

2,5-Deoxyfructosazine-13C4 (NSC 270912-13C4) is the 13C-labeled 2,5-Deoxyfructosazine. 2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50=~1.25 mM).

1246815-27-9

NSC 270912-13C4

12352005

DNA/RNA Synthesis; Isotope-Labeled Compounds

Cell Cycle/DNA Damage; Others

Others

OC[C@@H](O)[C@@H](O)[C@H](O)[13C]1=N[13CH]=[13C](C[C@H](O)[C@H](O)CO)N=[13CH]1

C8 13C4H20N2O7

308.27

[1]Henry, et al. Synthesis of water-compatible imprinted polymers of in situ produced fructosazine and 2,5-deoxyfructosazine. Talanta 99, 816-823 (2012) .

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W777675/

Isotope-Labeled Compounds

No Development Reported