(2R,3S,4R) -2- (Hydroxymethyl) tetrahydro.,,,....

(2R,3S,4R) -2- (Hydroxymethyl) tetrahydrothiophene-3,4-diol is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

190315-43-6

12352005

H315, H319, H320

Nucleoside Antimetabolite/Analog

Cell Cycle/DNA Damage

Cancer-programmed cell death

Cancer

98.74

H2O : 62.5 mg/mL (ultrasonic)

O[C@H]1CS[C@H](CO)[C@H]1O

C5H10O3S

150.20

H315, H319, H320

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-W048245/2R-3S-4R-2-Hydroxymethyl-tetrahydrothiophene-3-4-diol-SDS-MedChemExpress.pdf

Reference compound1

No Development Reported