3-Amino-5-hydroxybenzoëzuur

3-Amino-5-hydroxybenzoic acid is a biosynthetic precursor of the mC7N unit of ansamycin antibiotics, including ansatrienin A and geldanamycin, as well as the antitumor antibiotic mitomycin C. 3-Amino-5-hydroxybenzoic acid may be an early intermediate in the shikimic acid pathway from glucose[1][2].

76045-71-1

AHBA

12352005

H302, H315, H319, H335

Drug Intermediate

Others

Infection

99.83

DMSO : 100 mg/mL (ultrasonic)

O=C(C1=CC(N)=CC(O)=C1)O

C7H7NO3

153.14

H302, H315, H319, H335

[1]Mao Y, et al. Molecular characterization and analysis of the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces lavendulae NRRL 2564. Chem Biol. 1999 Apr;6 (4) :251-63.|[2]Floss HG, et al. The biosynthesis of 3-amino-5-hydroxybenzoic acid (AHBA), the precursor of mC7N units in ansamycin and mitomycin antibiotics: a review. J Antibiot (Tokyo) . 2011 Jan;64 (1) :35-44.

Room Temperature

RT, protect from light

http://file.medchemexpress.com/batch_PDF/HY-W077634/3-Amino-5-hydroxybenzoic-acid-SDS-MedChemExpress.pdf

Reference compound1

No Development Reported