3-Fenylindool
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
3-Phenylthiophene (Compound 25) is a CYP2A6 inhibitor with a Ki value of 3.3 μM. The Ki values for CYP2E1, CYP2B6, CYP2C9, and CYP2C19 are 9.7, 14, 112, and 107 μM respectively. It shows no significant inhibition on CYP3A4 and CYP2D6. 3-Phenylthiophene can be used in smoking cessation research[1].
2404-87-7
12352005
H302, H315, H319, H335
Cytochrome P450
Metabolic Enzyme/Protease
Neuroscience-Neuromodulation
Neurological Disease
95.0
S1C=CC(=C1)C2=CC=CC=C2
C10H8S
160.23
H302, H315, H319, H335
[1]Yano JK, et al. Synthetic inhibitors of cytochrome P-450 2A6: inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallization. J Med Chem. 2006 Nov 30;49 (24) :6987-7001.
Room Temperature
Store at room temperature 3 years
http://file.medchemexpress.com/batch_PDF/HY-W140208/
Reference compound2
No Development Reported
CYP2; CYP3
Beschrijving
3-Phenylthiophene (Compound 25) is a CYP2A6 inhibitor with a Ki value of 3.3 μM. The Ki values for CYP2E1, CYP2B6, CYP2C9, and CYP2C19 are 9.7, 14, 112, and 107
Specificaties
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