3-Hydroxyfenylazijnzuur-d5

2- (3-Hydroxyphenyl-2,4,6-d3) acetic-2,2-d2 acid is the deuterium labeled 3-Hydroxyphenylacetic acid. 3-Hydroxyphenylacetic acid is an orally active flavonoid metabolite produced by intestinal flora, with blood pressure-lowering activity. 3-Hydroxyphenylacetic acid can also inhibit ferroptosis by upregulating the expression of GPX4, thereby improving spermatogenic dysfunction in aged mice. In addition, abnormal levels of 3-Hydroxyphenylacetic acid are closely related to certain diseases, such as autism spectrum disorders.

12352005

Aldehyde Dehydrogenase (ALDH) ; Apoptosis; Endogenous Metabolite; Ferroptosis; Glutathione Peroxidase; Isotope-Labeled Compounds; Keap1-Nrf2; Reactive Oxygen Species (ROS)

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Metabolism-sugar/lipid metabolism

Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

O=C(O)C([2H])(C1=C([2H])C=C([2H])C(O)=C1[2H])[2H]

C8H3D5O3

157.18

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W001083S1/

Isotope-Labeled Compounds

No Development Reported

GPX4