3-Hydroxyvalproïnezuur
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
3-Hydroxyvalproic acid (3-Hydroxy VPA) is a metabolite of valproic acid. 3-Hydroxyvalproic acid is a weak inhibitor of enzymes related to the mitochondrial β-oxidation pathway. 3-Hydroxyvalproic acid is promising for research of diseases related to abnormal valproic acid metabolism[1][2][3].
58888-84-9
3-Hydroxy VPA
12352211
H302-H312-H332
Endogenous Metabolite
Metabolic Enzyme/Protease
Metabolic Disease
CCC(O)C(CCC)C(O)=O
C8H16O3
160.21
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
[1]Heinemeyer G, et al. Oxidation and glucuronidation of valproic acid in male rats--influence of phenobarbital, 3-methylcholanthrene, beta-naphthoflavone and clofibrate. Biochem Pharmacol. 1985 Jan 1;34 (1) :133-9.|[2]Prickett KS, et al. Metabolism of valproic acid by hepatic microsomal cytochrome P-450. Biochem Biophys Res Commun. 1984 Aug 16;122 (3) :1166-73.|[3]Bello-Ramírez AM, et al. Do structural properties explain the anticonvulsant activity of valproate metabolites? A QSAR analysis. Epilepsia. 2002 May;43 (5) :475-81.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W400421/
Reference compound2
No Development Reported
Beschrijving
3-Hydroxyvalproic acid (3-Hydroxy VPA) is a metabolite of valproic acid. 3-Hydroxyvalproic acid is a weak inhibitor of enzymes related to the mitochondrial β-ox
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