3-Methoxycatechol (standaard)

3-Methoxycatechol is intermediate for the antivascular agents combretastatin A-1 and combretastatin B-1. 3-Methoxycatechol promotes esophageal carcinogenesis in rats models[1][2].

934-00-9

12352005

Drug Intermediate

Others

Cancer

COC1=CC=CC(=C1O)O

C7H8O3

140.14

[1]Tao Y, et al., Altering toluene 4-monooxygenase by active-site engineering for the synthesis of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinone. J Bacteriol. 2004 Jul;186 (14) :4705-13.|[2]Hirose M, et al., Effects of sodium nitrite and catechol, 3-methoxycatechol, or butylated hydroxyanisole in combination in a rat multiorgan carcinogenesis model. Cancer Res.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W116576R/

Reference Standards