3-Methyluracil

3-Methyluracil (Compound 5) is a pyrimidine heterocyclic compound. 3-Methyluracil can be isolated from Cordyceps bassiana. 3-Methyluracil has anti-inflammatory activity. 3-Methyluracil inhibits Luciferase activity induced by NF-κB and AP-1 and reduces the mRNA levels of COX-2 and TNF-α. 3-Methyluracil can be used for inflammatory diseases research[1].

608-34-4

12352005

H351

COX; TNF Receptor

Apoptosis; Immunology/Inflammation

Inflammation/Immunology

95.0

O=C1C=CNC(=O)N1C

C5H6N2O2

126.12

H351

[1]Suh W, et al. Chemical Constituents Identified from Fruit Body of Cordyceps bassiana and Their Anti-Inflammatory Activity. Biomol Ther (Seoul) . 2017 Mar 1;25 (2) :165-170.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-W140956/3-Methyluracil-SDS-MedChemExpress.pdf

Reference compound2

No Development Reported

COX-2