3′-Oxoluteïne

3′-Oxolutein, a metabolite of dietary lutein, is an anti-inflammatory agent and antioxidant, 3′-Oxolutein mitigates the effects of glutamate-induced ROS production and proinflammatory cytokine secretions in SH-SY5Y cells. 3'-Oxolutein reduces glutamate-induced iron content and increases thiol levels. 3′-Oxolutein can be used for the study of inflammation[1].

23984-55-6

3'-Dehydrolutein; Philosamiaxanthin

12352211

Endogenous Metabolite; Reactive Oxygen Species (ROS)

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

COVID-19-immunoregulation

Inflammation/Immunology

CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/[C@@H]2C(C)(CC(C=C2C)=O)C)=C(C)C[C@@H](O)C1

C40H54O2

566.86

[1]Pap R, et al. Protective Effects of 3'-Epilutein and 3'-Oxolutein against Glutamate-Induced Neuronal Damage. Int J Mol Sci. 2023 Jul 26;24 (15) :12008.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W743769/

Natural Products

No Development Reported