3,3-dimethyl-1-butanol (standaard)

3,3-Dimethyl-1-butanol (Standard) is the analytical standard of 3,3-Dimethyl-1-butanol. This product is intended for research and analytical applications. 3,3-Dimethyl-1-butanol (DMB) is an orally active inhibitor of trimethylamine (TMA) and trimethylamine N-oxide (TMAO). 3,3-Dimethyl-1-butanol inhibits the signaling pathway of p65 NF-κB and TGF-β1/Smad3. 3,3-Dimethyl-1-butanol has potential applications in cardiovascular disease (CVD)[2][3].

624-95-3

Endogenous Metabolite; NF-κB; Reference Standards; TGF-beta/Smad

Metabolic Enzyme/Protease; NF-κB; Others; Stem Cell/Wnt; TGF-beta/Smad

Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease; Cancer

CC(C)(CCO)C

C6H14O

102.17

[1]Wang G, et al. 3,3-Dimethyl-1-butanol attenuates cardiac remodeling in pressure-overload-induced heart failure mice. J Nutr Biochem. 2020 Apr;78:108341. |[2]Mao J, et al. Repeated 3,3-Dimethyl-1-butanol exposure alters social dominance in adult mice. Neurosci Lett. 2021 Jul 27;758:136006. |[3]Hsu CN, et al. Maternal 3,3-Dimethyl-1-Butanol Therapy Protects Adult Male Rat Offspring against Hypertension Programmed by Perinatal TCDD Exposure. Nutrients. 2021 Aug 30;13 (9) :3041. |[4]Valiente M, et al. 1-Butanol and 3, 3-dimethyl-1-butanol as cosurfactants of the laurylsulfobetaine/water system[J]. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2001, 183: 235-246.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W012977R/

Reference Standards