(3S,4R) -ME-344
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1374524-84-1
Mitochondrial Metabolism, ROS
Metabolism, Immunology/Inflammation
(3S,4R) -ME-344 is the (3S,4R) -enantiomer of ME-344. As an inhibitor of mitochondrial heme oxygenase 1 (HO-1), ME-344 specifically binds to and alters the structure of HO-1, facilitating its translocation from the rough endoplasmic reticulum to mitochondria, but only in drug-sensitive cells like H460 and SHP-77. This compound reduces mitochondrial ATP production and induces reactive oxygen species (ROS), disrupting redox balance and mitochondrial function. ME-344 exhibits significant antitumor activity, making it useful in cancer research, such as for breast cancer.
CC1=C2C([C@H]([C@H](CO2)C3=CC=C(O)C=C3)C4=CC=C(O)C=C4)=CC=C1O
C22H20O4
348.39
Ice Packs
-20°C
Beschrijving
(3S,4R) -ME-344 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
ExactaCruz® Pipette Tip Reload System, 50-1250 μl, case
sc-201714
80 Racks/Case
Disc Membrane Hydrophobic PTFE, 0.22μm
CPTB14222
50 PCS
Rat Serum Albumin
CSB-NP000101r-01
1 mg
Denhardt's Solution (50X)
EC-915
50 mL
FKBP4, ID (FK506-binding Protein 4, Peptidyl-prolyl cis-trans Isomerase FKBP4, PPIase FKBP4, Rotamase, HSP-binding Immunophilin, HBI, FKBP52 Protein, 52kD FK506-binding Protein, 52kD FKBP, FKBP-52, 59kD Immunophilin, FKBP59, p59 Protein, FKBP-4, FKBP52)
MBS623609-01
0.2 mL
West Nile Virus, NS3 Protease (WNV)
MBS603723-01
0.1 mg
Human Sertoli Cell Complete Medium
MBS2576755-01
100 mL
Urobilinogen protein
MBS5303823-01
100 mg
Recent gezochte producten
ExactaCruz® Pipette Tip Reload System, 50-1250 μl, case
sc-201714
80 Racks/Case
Cbp 3'UTR Luciferase Stable Cell Line
TU201714
1.0 mL
Mouse Gpx2 activation kit by CRISPRa
GA201714
1 Kit
CCDC50 Human qPCR Template Standard (NM_174908)
HK201714
1 Kit
Prpsap2 Mouse qPCR Template Standard (NM_144806)
MK201714
1 Kit
Horse Prekallikrein Affinity Purified
B2017141
50 µg
Human Recombinant Activin A
B2017149
10 µg
Mouse Alpha-N-acetyl-neuraminyl-2, 3-beta-galactosyl-1, 3-N-acetyl-galactosaminide alpha-2, 6-sialyltransferase (ST6GALNAC4) ELISA Kit
MBS7201714-01
48 Well