4-Amino-TEMPO-d17

4-Amino-TEMPO-d17 (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d17) is the deuterium labeled 4-Amino-TEMPO. 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others[1][2].

70588-04-4

4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d17

12352005

Biochemical Assay Reagents; Isotope-Labeled Compounds

Others

Inflammation/Immunology

10 mM in DMSO

[O]N1C(C([2H])([2H])[2H])(C([2H])([2H])C(C([2H])([2H])C1(C([2H])([2H])[2H])C([2H])([2H])[2H])([2H])N)C([2H])([2H])[2H]

C9H2D17N2O

188.36

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Gergely M, et al. 4‐Amino‐TEMPO as N‐Nucleophile in Palladium‐Catalyzed Aminocarbonylation. Journal of Heterocyclic Chemistry, 2017, 54 (1) : 634-640.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W002004S1/

Isotope-Labeled Compounds

No Development Reported