4-Chloor-2- (trifluoracetyl) aniline
Gecertificeerd

4-Chloor-2- (trifluoracetyl) aniline

Catalog #: HY-W023836-01
Maat: 100 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100

Technische Specificaties

Description

4-Chloro-2- (trifluoroacetyl) aniline (Compound 10), an analog of Efavirenz , is a Pregnane X receptor (PXR) ligand. 4-Chloro-2- (trifluoroacetyl) aniline has no PXR activation activity without induction of Cyp3a11 mRNA expression[1].

CAS Number

154598-53-5

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Derivative; Pregnane X Receptor (PXR)

Related Pathways

Others; Vitamin D Related/Nuclear Receptor

Field of Research

Others

Purity

97.0

Smiles

O=C(C1=CC(Cl)=CC=C1N)C(F)(F)F

Molecular Formula

C8H5ClF3NO

Molecular Weight

223.58

Precautions

H302, H315, H319, H335

References & Citations

[1]Narayanan B, et al. Probing Ligand Structure-Activity Relationships in Pregnane X Receptor (PXR) : Efavirenz and 8-Hydroxyefavirenz Exhibit Divergence in Activation. ChemMedChem. 2018 Apr 6;13 (7) :736-747.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W023836/

Scientific Category

Reference compound2

Clinical Information

No Development Reported

Beschrijving

4-Chloro-2- (trifluoroacetyl) aniline (Compound 10), an analog of Efavirenz , is a Pregnane X receptor (PXR) ligand. 4-Chloro-2- (trifluoroacetyl) aniline has n

Specificaties

Productnaam4-Chloor-2- (trifluoracetyl) aniline
Categorie
Beschikbare grootte100 mg
CatalogusnummerHY-W023836-01