4-Diethylaminobenzaldehyde (standaard)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenases (ALDHs) inhibitor, with a Ki of 4 nM for ALDH1. 4-Diethylaminobenzaldehyde displays potent anti-androgenic effect (IC50= 1.71μM) [1][2].
120-21-8
12352005
Aldehyde Dehydrogenase (ALDH)
Metabolic Enzyme/Protease
Cancer
O=CC1=CC=C(N(CC)CC)C=C1
C11H15NO
177.25
[1]Luo M, et al. Diethylaminobenzaldehyde is a covalent, irreversible inactivator of ALDH7A1. ACS Chem Biol. 2015 Mar 20;10 (3) :693-7.|[2]Araki N, et al. Screening for androgen receptor activities in 253 industrial chemicals by in vitro reporter gene assays using AR-EcoScreen cells. Toxicol In Vitro. 2005 Sep;19 (6) :831-42.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W016645R/
Reference Standards
Beschrijving
4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenases (ALDHs) inhibitor, with a Ki of 4 nM for ALDH1. 4-Diethylaminobenzaldehyde displays potent an
Specificaties
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