4-Epitetracycline-d6

4-Epitetracycline-d6 is deuterated labeled 4-Epitetracycline hydrochloride 4-Epitetracycline hydrochloride is an epimer of Tetracycline (HY-A0107). Tetracycline can undergo epimerization insolution to 4-Epitetracycline hydrochloride, which shows a much lower antibiotic activity.

12352005

Antibiotic; Isotope-Labeled Compounds

Anti-infection; Others

COVID-19-immunoregulation

Infection

10 mM in DMSO

OC1=C(C2=CC=C1)C(C3=C([C@@](O)([C@]4(C[C@@]3([C@@]2(O)C)[H])[H])C(C(C(N)=O)=C([C@@H]4N(C([2H])([2H])[2H])C([2H])([2H])[2H])O)=O)O)=O

C22H18D6N2O8

450.47

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Lin Z, et al. Effects of two ecological earthworm species on tetracycline degradation performance, pathway and bacterial community structure in laterite soil. J Hazard Mater. 2021 Jun 15;412:125212.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W701205/

Isotope-Labeled Compounds

No Development Reported