4-Hydroxyduloxetine β-D-glucuronide (natrium)

4-Hydroxy duloxetine β-D-glucuronide (4-Hydroxy duloxetine glucuronide) sodium is a major metabolite of Duloxetine. 4-Hydroxy duloxetine β-D-glucuronide sodium is promising for research of hepatic or renal impairment[1].

4-Hydroxy duloxetine glucuronide (sodium) ; LY550408 (sodium)

12352005

Drug Metabolite

Metabolic Enzyme/Protease

Metabolism-protein/nucleotide metabolism

Metabolic Disease

O[C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O)OC2=C3C=CC=CC3=C(C=C2)O[C@H](C4=CC=CS4)CCNC)C(O[Na])=O

C24H26NNaO8S

511.52

[1]Knadler MP, et al. Duloxetine: clinical pharmacokinetics and drug interactions. Clin Pharmacokinet. 2011 May;50 (5) :281-94.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W766140/

Reference compound1

No Development Reported