4-Hydroxyfenylpyruvinezuur (standaard)

4-​Hydroxyphenylpyruvic acid (Standard) is the analytical standard of 4-​Hydroxyphenylpyruvic acid. This product is intended for research and analytical applications. 4-Hydroxyphenylpyruvic acid is an intermediate in the metabolism of the amino acid phenylalanine. 4-Hydroxyphenylpyruvic acid is a substrate of 4-hydroxyphenylpyruvic acid dioxygenase. 4-Hydroxyphenylpyruvic acid can be used in the study of HPD-related diseases, such as type III tyrosinemia and hawkinsinuria[1][2].

156-39-8

12352005

H315, H319

Endogenous Metabolite; Reference Standards

Metabolic Enzyme/Protease; Others

Metabolic Disease

96.44

O=C(O)C(CC1=CC=C(O)C=C1)=O

C9H8O4

180.16

H315, H319

[1]Brand LM, et al. Effect of glucagon on phenylalanine metabolism and phenylalanine-degrading enzymes in the rat. Biochem J. 1974 Aug;142 (2) :231-45.|[2]Tomoeda K, et al. Mutations in the 4-hydroxyphenylpyruvic acid dioxygenase gene are responsible for tyrosinemia type III and hawkinsinuria. Mol Genet Metab. 2000 Nov;71 (3) :506-10.

Blue Ice

-20°C, sealed storage, away from light and moisture

http://file.medchemexpress.com/batch_PDF/HY-W010040R/4-Hydroxyphenylpyruvic-acid-Standard-SDS-MedChemExpress.pdf

Reference Standards

No Development Reported