4-Hydroxyisoftaalzuur

4-Hydroxyisophthalic acid activates antioxidant enzymes (such as catalase CAT and superoxide dismutase SOD), scavenges free radicals, and exhibits antioxidant property. 4-Hydroxyisophthalic acid activates AChE and BChE, enhances neuronal function and improves Tau-induced neurobehavioral defects. 4-Hydroxyisophthalic acid improves the cognitive defects, and ameliorates circadian rhythm disorders of fruit flies[1].

636-46-4

12352005

H315, H319, H335

Cholinesterase (ChE) ; SOD

Immunology/Inflammation; Neuronal Signaling

Neurological Disease

99.57

DMSO : ≥ 100 mg/mL

O=C(O)C1=CC(C(O)=O)=CC=C1O

C8H6O5

182.13

H315, H319, H335

[1]Haddadi M, et al., 4-Hydroxyisophthalic acid from Decalepis hamiltonii rescues the neurobehavioral deficit in transgenic Drosophila model of taupathies. Neurochem Int. 2016 Nov;100:78-90.

Room Temperature

Store at room temperature 3 years

http://file.medchemexpress.com/batch_PDF/HY-76632/4-Hydroxyisophthalic-acid-SDS-MedChemExpress.pdf

Reference compound1

No Development Reported