4-Hydroxyvalsartan
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
4-Hydroxy valsartan is a metabolite of Valsartan. 4-Hydroxy valsartan regulates the expression of platelet surface receptors and inhibits conventional plasma or whole blood collagen induced platelet aggregation. 4-Hydroxy valsartan has antiplatelet activity[1].
188259-69-0
Valeryl-4-hydroxyvalsartan; CGP 71580
12352005
Drug Metabolite
Metabolic Enzyme/Protease
Cardiovascular Disease
O=C(N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NN=NN3)[C@@H](C(C)C)C(O)=O)CCC(C)O
C24H29N5O4
451.52
[1]Serebruany VL, et al. Effects of valsartan and valeryl 4-hydroxy valsartan on human platelets: a possible additional mechanism for clinical benefits. J Cardiovasc Pharmacol. 2004 May;43 (5) :677-84.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W699533/
Reference compound1
No Development Reported
Beschrijving
4-Hydroxy valsartan is a metabolite of Valsartan. 4-Hydroxy valsartan regulates the expression of platelet surface receptors and inhibits conventional plasma or
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