4-Methylamfetamine (hydrochloride)

4-Methylamphetamine hydrochloride is a 5-HT1A receptor agonist that induces hypothermia in rats by binding to the 5-HT1A receptor. Additionally, 4-Methylamphetamine hydrochloride acts on norepinephrine (NE), dopamine (DA), and serotonin (5-HT) transporters to increase the extracellular levels of these neurotransmitters. 4-Methylamphetamine hydrochloride can be used in the study of neurological disorders[1][2].

41632-56-8

4-MA (hydrochloride)

12352005

H302, H315, H319, H335

5-HT Receptor; Dopamine Receptor; Monoamine Transporter

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Neuroscience-Neuromodulation

Neurological Disease

99.86

H2O : 125 mg/mL (ultrasonic)

NC(CC1=CC=C(C)C=C1)C.Cl

C10H16ClN

185.69

H302, H315, H319, H335

[1]Rubio M, et al. Serotonin is involved in the psychostimulant and hypothermic effect of 4-methylamphetamine in rats. Neurosci Lett. 2015 Mar 17;590:68-73. |[2]Blanckaert P, et al. 4-Methyl-amphetamine: a health threat for recreational amphetamine users. J Psychopharmacol. 2013 Sep;27 (9) :817-22.

Room Temperature

4°C (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-W417914/4-Methylamphetamine-hydrochloride-SDS-MedChemExpress.pdf

Reference compound1

No Development Reported

5-HT1 Receptor