4-Methylthiazool

4-Methylthiazole is an Apoptosis trigger. 4-Methylthiazole markedly reduces CD45 and CD123 surface markers, increases ROS levels, Caspase-3 protein levels. 4-Methylthiazole triggers Apoptosis and mitochondrial disruption. 4-Methylthiazole can be used in the research of acute promyelocytic leukemia[1].

693-95-8

12352200

H226, H302, H315, H318, H335

Apoptosis; Caspase; Mitochondrial Metabolism; Reactive Oxygen Species (ROS)

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Cancer-programmed cell death

Cancer

99.96

10 mM in DMSO

CC1=CSC=N1

C4H5NS

99.15

H226, H302, H315, H318, H335

[1]Meriç N, et al. 4-Methylthiazole triggers apoptosis and mitochondrial disruption in HL-60 cells. Mol Biol Rep. 2024 Sep 19;51 (1) :997.

Room Temperature

Store at room temperature 3 years

http://file.medchemexpress.com/batch_PDF/HY-W001245/

Biochemical Assay Reagents

No Development Reported

Caspase 3