4-Piperidyl-N- (2-bifenyl) carbamaat
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
4-Piperidyl N- (2-biphenyl) carbamate (compound MA) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist. 4-Piperidyl N- (2-biphenyl) carbamate exhibits higher affinity for M2 and M3 mAChR than β2AR (M2 pKi = 7.33; M3 pKi = 7.51; β2AR pKi = 4.94) [1].
171722-92-2
12352005
H302, H315, H319, H335
MAChR
GPCR/G Protein; Neuronal Signaling
Inflammation/Immunology
99.80
O=C(OC1CCNCC1)NC=2C=CC=CC2C=3C=CC=CC3
C18H20N2O2
296.37
H302, H315, H319, H335
[1]Steinfeld T, et al. THRX-198321 is a bifunctional muscarinic receptor antagonist and beta2-adrenoceptor agonist (MABA) that binds in a bimodal and multivalent manner. Mol Pharmacol. 2011 Mar;79 (3) :389-99.
Room Temperature
4°C (Powder, protect from light)
http://file.medchemexpress.com/batch_PDF/HY-W076756/4-Piperidyl-N-2-biphenyl-carbamate-SDS-MedChemExpress.pdf
Reference compound2
No Development Reported
MAChR2; mAChR3
Beschrijving
4-Piperidyl N- (2-biphenyl) carbamate (compound MA) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist. 4-Piperidyl N- (2-biphenyl) carbamate
Specificaties
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