4-propylfenol

4-Propylphenol is a plant-derived phenolic compound. 4-Propylphenol causes an increase in ROS within the Fusarium graminearum cells, leading to damage to the DNA and cell membranes of the mycelia, effectively inhibiting the growth of the mycelia. 4-Propylphenol also has a growth inhibitory effect on walnut pathogenic fungi (C. gloeosporioides, C. siamense, A. alternata), with its EC50 ranging from 29.11 to 31.89 mg/L, and it also inhibits spore germination, with EC50 being 55.04-71.85 mg/L. 4-Propylphenol can be used in the research of fungal diseases in walnuts and wheat Fusarium head blight[1][2].

645-56-7

12352005

H302+H312+H332, H315, H318, H335, H412

DNA/RNA Synthesis; Fungal; Reactive Oxygen Species (ROS)

Anti-infection; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

COVID-19-anti-virus

Infection

99.87

OC1=CC=C(C=C1)CCC

C9H12O

136.19

H302+H312+H332, H315, H318, H335, H412

[1]Sun S, et al. Antifungal Activity and Mechanism of 4-Propylphenol Against Fusarium graminearum, Agent of Wheat Scab, and Its Potential Application. J Agric Food Chem. 2024 Mar 13;72 (10) :5258-5268.|[2]Yu X, et al. 4-Propylphenol Alters Membrane Integrity in Fungi Isolated from Walnut Anthracnose and Brown Spot. J Fungi (Basel) . 2025 Aug 22;11 (9) :610.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-W017611/

Reference compound2

No Development Reported