4,4?-Secalonzuur D
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2265910-52-7
Reactive Oxygen Species, PARP, Pyroptosis, Caspase, Apoptosis
Immunology/Inflammation, NF-κB, Metabolism, Apoptosis, Proteases/Proteasome, Chromatin/Epigenetic, DNA Damage/DNA Repair
4,4′-Secalonic acid D (Compound 12) is a PARP1 inhibitor. By inhibiting PARP1, 4,4′-Secalonic acid D induces the accumulation of ROS and DNA damage, activating the caspase-3/GSDME pathway, which leads to tumor cell apoptosis (apoptosis) and pyroptosis (pyroptosis) . It exhibits antitumor activity.
C(OC)(=O)[C@]12C(C(=O)C=3C(O1)=C(C=CC3O)C4=C5C(C(=O)C=6[C@@](C(OC)=O)(O5)[C@H](O)[C@@H](C)CC6O)=C(O)C=C4)=C(O)C[C@H](C)[C@H]2O
C32H30O14
638.572
Ice Packs
-20°C
Beschrijving
4,4?-Secalonzuur D Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
Biotin-Recombinant (sf9) Marburg virus glycoprotein (Musoke, HA-tag, >95%), purified
MVGP16-BTN
100 µL
MARV VP40/Marburg VP40 Protein (N-His, Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980) ) )
P505862
100 µg
Hettich Centrifuge Rotanta 460R Refrigerated Large Volume
CEN0703
1 Each
X4RF Refrigerated Centrifuge
75009936
1 Each
Drug Stability Chamber
500-DSC102
1 Unit
Modular Incubator Chamber
MIC-101
1 Unit
CYP707A2 Antibody
GTR17947107
2 mg
SsDNA Assay Kit
12645ES60
100 Tests
Recent gezochte producten
Biotin-Recombinant (sf9) Marburg virus glycoprotein (Musoke, HA-tag, >95%), purified
MVGP16-BTN
100 µL
MARV VP40/Marburg VP40 Protein (N-His, Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980) ) )
P505862
100 µg
X4RF Refrigerated Centrifuge
75009936
1 Each
Low Speed Refrigerated Centrifuge
LX104LSR
1 Unit
Low Speed Refrigerated Centrifuge
LX117LSR
1 Unit
Low Speed Refrigerated Centrifuge
LX124LSR
1 Unit
Blood Bank Refrigerator
LX4000BBR
1 Unit
Blood Bank Refrigerator
LX4002BBR
1 Unit