5β-Dihydroprogesteron

5β-Dihydroprogesterone (5βDHP) is the metabolite of Progesterone. 5β-Dihydroprogesterone binds to oxytocin receptor, reduces the Oxytocin (HY-17571) -induced calcium signal transduction, thereby exhibiting the tocolytic activity[1].

128-23-4

5βDHP

12352211

H302, H315, H319, H335

Oxytocin Receptor

GPCR/G Protein

Endocrinology

99.94

DMSO : 33.33 mg/mL (ultrasonic)

C[C@@]12[C@]3([H])[C@](CC[C@]1([H])CC(CC2)=O)([H])[C@@]4([H])[C@](CC3)([C@H](CC4)C(C)=O)C

C21H32O2

316.48

H302, H315, H319, H335

[1]Sheehan PM, et al., 5 Beta-dihydroprogesterone and steroid 5 beta-reductase decrease in association with human parturition at term. Mol Hum Reprod. 2005 Jul;11 (7) :495-501.

Blue Ice

-20°C (Powder, stored under nitrogen)

http://file.medchemexpress.com/batch_PDF/HY-W587861/5β-Dihydroprogesterone-SDS-MedChemExpress.pdf

Natural Products

No Development Reported