5-HT2A-agonist 3

5-HT2A agonist 3 (Compound P-141) is a selective 5-hydroxytryptamine 2A receptor (5-HT2A) agonist with an EC50 value of 13.80 nM. 5-HT2A agonist 3 is promising for research of mental illnesses such as depression, post-traumatic stress disorder, obsessive-compulsive disorder, and central nervous system disorders[1].

2945111-66-8

12352005

5-HT Receptor

GPCR/G Protein; Neuronal Signaling

Neurological Disease

OC1=CC=CC2=C1C(CCN(C(C)C)CCC)=CN2

C16H24N2O

260.37

[1]Sabnis RW, et al. Novel Compounds as 5-HT2A Agonists for Treating Mental Illness or CNS Disorders. ACS Med Chem Lett. 2025 Feb 11;16 (3) :377-378.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W1123900/

Reference compound1

No Development Reported

5-HT2 Receptor