5-Hydroxymethyluracil (standaard)

5-Hydroxymethyluracil is a product of oxidative DNA damage. 5-Hydroxymethyluracil can be used as a potential epigenetic mark enhancing or inhibiting transcription with bacterial RNA polymerase.

4433-40-3

12352005

Endogenous Metabolite

Metabolic Enzyme/Protease

Others

O=C1NC(C(CO)=CN1)=O

C5H6N2O3

142.11

[1]Djuric Z, et al. Quantitation of 5- (hydroxymethyl) uracil in DNA by gas chromatography with mass spectral detection. Chem Res Toxicol. 1991 Nov-Dec;4 (6) :687-91.|[2]Janoušková M, et al. 5- (Hydroxymethyl) uracil and -cytosine as potential epigenetic marks enhancing or inhibiting transcription with bacterial RNA polymerase. Chem Commun (Camb) . 2017 Dec 12;53 (99) :13253-13255.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W004924R/

Reference Standards